https://www.selleckchem.com/pr....oducts/PF-2341066.ht
In contrast, miR-182-3p mimic and Myadm gene knockout attenuated the changes in the hemodynamics and structure of the cardio-pulmonary system in MCT-induced PAH in rats. Myadm mediated the proliferation of pulmonary artery smooth muscle cells (PASMCs) by altering the cell cycle kinase inhibitor (p21/Cip1) expression through the transcription factor Krüppel-like factor 4 (KLF4) translocation into the cytoplasm. Conclusion Our findings indicate the prognostic and therapeutic significance of miR-182-3p in PAH and provide a new regulator
Like
Comment
Share