https://paxsignals.com/index.p....hp/multi-functional-
The IPR is managed by PALS-22 and PALS-25, proteins of unknown biochemical function, which regulate expression of genetics induced by normal intracellular pathogens. We previously indicated that PALS-22 and PALS-25 regulate the mRNA appearance of the predicted ubiquitin ligase component cullin cul-6, which promotes thermotolerance in pals-22 mutants. Nevertheless, it had been unclear whether CUL-6 acted alone, or together with various other cullin-ring ubiquitin ligase component
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