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The functional group threshold for the isolate with unprotected and protected β-aminonitriles, structural analogues of β-hydroxynitriles has also been investigated with disappointingly poor separated yields and selectivity obtained. The isolate had been additional evaluated utilizing the α- aminonitrile phenylglycinonitrile generating acid in exceptional yield and ee (99 % (S) - isomer and 50 % yield). A series of pH studies with this substrate suggested pH 7 to be the optimum pH to avoid p
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