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In addition, stem-like cells also seem to represent part of the CAFs. BACKGROUND/AIM Uterine leiomyosarcoma (Ut-LMS) is a refractory tumor that repeatedly recurs with hematogenous metastasis, which might be as a result of the existence of drug-resistant cyst stem cells. Its treatment is restricted to surgical procedures. We previously reported that Ut-LMS spontaneously created in mice deficient within the proteasome component low-molecular size p

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