https://www.selleckchem.com/pr....oducts/fenretinide.h
Continuous docetaxel (DTX) treatment of non-small cell lung cancer induces development of drug resistance, but the mechanism is poorly understood. In this study we performed metabolomics analysis to characterize the metabolic patterns of sensitive and resistant A549 non-small cell lung cancer cells (A549/DTX cells). We showed that the sensitive and resistant A549 cells exhibited distinct metabolic phenotypes the resistant cells were characterized by an altered microenvironment of redox homeostasis with reduced glutathione and elevat
Like
Comment
Share
