https://www.selleckchem.com/pr....oducts/verubecestat.
To test our model, we compare its predictions with measured distributions of paxillin in spreading fibroblasts.Experimental evidence for age-dependent loss of intracellular water content as a widespread concomitant of cellular senescence is reviewed. Quantitative models are presented, indicating that an age-dependent increase in macromolecular crowding resulting from water loss may be responsible for three observed phenomena a general age-dependent loss of intracellular protein solubility, a delayed and rapid appearance of high mol
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