https://www.selleckchem.com/pr....oducts/ne-52-qq57.ht
The linker of the nucleoskeleton and cytoskeleton (LINC) complex is composed of two transmembrane proteins the KASH domain protein localized to the outer nuclear membrane and the SUN domain protein to the inner nuclear membrane. In budding yeast, the sole SUN domain protein, Mps3, is thought to pair with either Csm4 or Mps2, two KASH-like proteins, to form two separate LINC complexes. Here, we show that Mps2 mediates the interaction between Csm4 and Mps3 to form a heterotrimeric telomere-associated LINC (t-LINC) complex in budding ye
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