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In combination, risk compensation and viral adaptation can, under certain scenarios, reverse initial declines in prevalence due to vaccination, and result in HIV prevalence at 15 years equal to or greater than prevalence without a vaccine.The cratonic elements of proto-Australia, East Antarctica, and Laurentia constitute the nucleus of the Palaeo-Mesoproterozoic supercontinent Nuna, with the eastern margin of the Mawson Continent (South Australia and East Antarctica) positioned adjacent to the western margin of Laurentia. Such reconstruc