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Considering a pilot study we picked from 1016 consecutive patients known our Centre for 'difficult-to-treat' hypertension those with RH, for an observational prospective cohort research. We excluded those non-adherent to therapy (by therapeutic medicine tracking) and those with pseudo-RH (by 24-h BP monitoring), which left 110 customers which came across the European community of Cardiology/European community of Hypertension (ESC/ESH) 2013 definition for RH. Of the customers, 77 had been pos