https://www.selleckchem.com/pr....oducts/rogaratinib.h
This review draws together the most recent findings in ALS biomarker research from biochemical, imaging and neurophysiology techniques. The potential of circulating RNA is highlighted, including new retrieval techniques. With ongoing genetic clinical trials, the need for pharmacodynamic biomarkers is essential. There is a strong case for neurofilament proteins being validated in ALS; their biomarker profile is discussed. Oxidative stress and neuroinflammation studies offer insight into disease mechanisms and offer good biomarker pot
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