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Next, by co-incubating the exogenous miR-139-5p mimics with Fusobacterium nucleatum, we proved that exogenous miR-139-5p could inhibit the proliferation of Fusobacterium nucleatum. After treating CRC cells with Fusobacterium nucleatum, which incubated with miR-139-5p mimics in advance, MTT assay indicated that the stimulation of Fusobacterium nucleatum was weakened. Besides, we speculated the binding site between miR-139-5p and Fusobacterium nucleatum. In sum, our study suggests a new prospect for the treatment of CRC, and the combination
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