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The reliability studies yielded encouraging results even after 50th cycle of photodegradation. The effect of catalyst loading on the photodegradation efficacy has also been studied.This work discuss a simple, rapid, accurate, precise, sensitive, validated and effective cost spectrofluorometric method. The technique was applied for the analysis of fingolimod hydrochloride (FIN) in pure form, capsules, human plasma and urine samples. Formation of binary complex between the suggested amino group of (FIN) with Eosin Y (EOY) is the principle