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84%). The present work represents an attempt to find new and realiable treatment modalities to enhance the efficacy based on the adjuvant therapy of preexisting drugs/interventions with PA. According to our results, the combination allopurinol-PA is the most effective adjuvant therapy. The application of cryotherapy and TCA stand as useful and encouraging suplementary interventions. The combination imiquimod-PA and pentoxifylline add no additional benefit The results of this work may be helpful in devising and modify the current guidelin
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