https://www.selleckchem.com/pr....oducts/vps34-inhibit
The results of bioinformatics analysis and dual luciferase reporter gene assay showed that LINC00488 could directly bind to miR-376a-3p and down-regulated the expression level of miR-376a-3p. In addition, Paraoxonase-2 (PON2) was a target gene of miR-376a-3p and negatively regulated by miR-376a-3p. Rescue experiment indicated that LINC00488 might enhance PON2 expression by sponging miR-376a-3p in thyroid cancer. Taken together, our study revealed that lncRNA LINC00488 acted as an oncogenic gene in the progression of thyroid ca
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