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The biochemical variables (blood sugar, fat, Scr, BUN, UA, U-Alb and UAE) were analyzed. The pathological changes in renal tissue were seen by histological staining with HE and Masson. The effectation of EHF in the proliferation of NRK-49F cells ended up being analyzed by CCK-8 assay andosis of this structure. These results might have clinical ramifications to treat DN. Copyright © 2020 Shen, Jiang, Li, Wang, Ma, Zhang, Zhu, Rahman, Zhang, Luan and Zhang.Dl-3-n-butylphthalide (dl-NBP)