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The findings of this study will aid uptake of the guideline and inform improvement efforts for other international optometric guidelines. The overall and domain specific quality of the AOA 2019 guideline was high, however, improvement in its applicability domain is required. The findings of this study will aid uptake of the guideline and inform improvement efforts for other international optometric guidelines.The search for a suitable material to promote regeneration after long-distance peripheral nerve defects turned the spotlight

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