https://www.selleckchem.com/pr....oducts/senaparib.htm
The data presented here enhance our understanding of the functional contributions of ligand binding at the α4α4 subunit interface to (α4)3(β2)2 nAChR-channel gating. These findings support the potential use of α4α4 specific ligands to increase the efficacy of the neurotransmitter ACh in conditions associated with decline in nAChRs activity in the brain.Well-orchestrated maternal-fetal cross talk occurs via secreted ligands, interacting receptors, and coupled intracellular pathways between the conceptus and endometrium and is essential