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Biochemical parameters including diabetic, inflammatory and antioxidant biomarkers had been evaluated. Brain histopathology has also been carried out. Results unveiled considerable increase in sugar, AGE, aldose reductase with insulin decrease in diabetic neuropathy induced team when compared with healthier control. Additionally, inflammatory markers increased significantly in diabetic neuropathy induced group. An amazing change in oxidative status ended up being seen in the same team.

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