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Herein, we reported a photoluminescent nanosensor for MeHg+ detection in brain by integrating the bioimaging of gold nanoclusters (Au NCs), the fluorescence of Au NCs quenched by MeHg+, while the brain focusing on feature of your recently constructed 16-mer shell-like protein (7A). Initially, Au NCs with 7A as a biotemplate (7A-Au NCs) by a facile and green technique in water are fabricated for the first time, the fluorescence of which (∼650 nm) is quenched by MeHg+ in a dose-dependent manner in vitro. Second, t
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