https://histonedemethylase-sig....nal.com/index.php/br
The chemical design of NNRTIs changed in the last few years as a result to resistance associated mutations (RAMs) and opposition. NNRTIs tend to be chemically diverse compounds that bind an allosteric website of HIV RT. Resistance-associated mutations (RAMs) identified in HIV clients tend to be associated with NNRTI resistance. RAMs confer amino acid modifications that change both structural and physiochemical properties associated with the allosteric site. Finally
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