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vity, specificity, precision and negative predictive value for that method are 0.98, 1, 0.962, 0.96, and 0.962, respectively. In this paper, by feeding norm values of protein dimers into support vector machines in different accessible surface area thresholds, we demonstrate that even small number of proteins in pairs of multiple alignments could allow one to accurately discriminate between positive and negative dimers. In this paper, by feeding norm values of protein dimers into support vector machines in different access