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The BEI was attenuated in the nT2D group in supine rest and throughout HUTT compared with normoglycemic and prediabetes groups. The multivariable linear regression analysis showed that BEI was associated with fasting glucose (β =  - 0.52, p  0.001) and HbA1c (β =  - 0.57, p 0.001) independently of cardiovascular risk factors. Cardiovascular autonomic neuropathy, expressed as blunted BEI, is the only abnormal autonomic nervous test detected in nT2D, and it was independently associated with fasting glucose and HbA1c values. Cardiovascular auto

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