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757). The mean difference of corrected NSE and initial NSE was 1.92%, the SD of difference was 5.23%, and furthermore, the difference was independent of tendency of HI (Spearman r=-0.069, p=0.64. The 95% confidence interval of mean difference (from -8.33% to 12.17%) was less than the acceptable bias range (±20%). The agreement between individual correction equation and NSE assay was satisfied. Our automated processing algorithm for serum NSE could provide efficient management of posttest data and correct positive bias from specimen h