https://www.selleckchem.com/pr....oducts/10-dab-10-dea
This pattern was present in patients across a broad range of injury severities. CONCLUSIONS After major trauma, there seems to be an early 'antifibrinolytic gap' with the natural antifibrinolytic system lagging several hours behind the natural profibrinolytics. An early dose of exogenous antifibrinolytic (TXA) might have its effect by filling this gap. The finding that tPA and subsequent clot breakdown (illustrated by D-dimer formation) are raised in a broad range of patients, with little correlation between the initi
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