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ef thermal pain stimulus. Although attention was not directly measured, the pattern of pain ratings, presence ratings, and fun ratings are consistent with an attentional mechanism for how VR reduces pain. Whether the current results generalize to clinical patient populations is another important topic for future research. Additional research and development is recommended. Copyright © 2020 Al-Ghamdi, Meyer, Atzori, Alhalabi, Seibel, Ullman and Hoffman.Physical activity (PA) promotes neurogenesis and has neuroprotective effects on the bra