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https://www.selleckchem.com/pr....oducts/jnk-inhibitor
Radiation therapy (RT)-induced lymphopenia (RIL) is linked with inferior survival in esophageal and pancreatic cancers. Previous work has demonstrated a correlation between spleen dose and RIL risk. The present study correlates spleen dose-volume parameters with fractional lymphocyte loss rate (FLL) and total percent change in absolute lymphocyte count (%ΔALC) and suggests spleen dose constraints to reduce RIL risk. This registry-based study included 140 patients who underwent RT for pancreatic (n = 67), gastroesophageal (n =

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