https://www.selleckchem.com/pr....oducts/rhps4-nsc7141
Current data regarding the roles of branched-chain amino acids (BCAA) in metabolic health are rather conflicting, as positive and negative effects have been attributed to their intake. To address this, individual effects of leucine and valine were elucidated in vivo (C57BL/6JRj mice) with a detailed phenotyping of these supplementations in high-fat (HF) diets and further characterization with in vitro approaches (C2C12 myocytes). Here, we demonstrate that under HF conditions, leucine mediates beneficial effects on adiposity and
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