https://www.selleckchem.com/pr....oducts/pf-06463922.h
© FEMS 2020.Continuous efforts have been invested in the selective modification of proteins. Herein, we first report the construction of sulfonium tethered cyclic peptides via an intramolecular cyclization by an aliphatic halide. This cyclization could enhance the stability and cellular uptake of peptides. Furthermore, the sulfonium center could be recognized by cysteine in the vicinity of the protein-peptide interacting interface and form a peptide-protein conjugate.Second near-infrared window (NIR-II, 1000-1700 nm) absorption and