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An excellent correlation (r2 = 0.8 for methadone permeation ended up being gotten between porcine ear skin and personal skin data. Solvent uptake studies suggested that the current presence of PG not only increased methadone permeation but in addition TC permeation. The medicine seems to "track" the permeation of TC. Future researches will expand more the range of potential cars for optimal delivery regarding the medication, that will fundamentally becoming investigated
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