https://www.selleckchem.com/pr....oducts/shp099-dihydr
7% [182/310] vs 45.2% [94/208]). In day 2 nonresponders, 54.9% vs 44.3% (ESK + AD vs AD + PBO, respectively) achieved response at day 28 (P less then .01). Similarly, among day 2 and 8 nonresponders, 52.1% vs 42.4% achieved response by day 28 (P = .01). In nonresponders at day 2 and at days 2 and 8, the odds ratio for a response at day 28 was 1.61 (95% CI, 1.09-2.4 with ESK + AD versus 1.56 (95% CI, 1.04-2.35) with AD + PBO.Conclusions Patients with TRD without a demonstrated response within the first week of treatmen
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