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Pi values of NAP and RTV across the W/O interface are found to be sensitive to (1) the molecule surface area, molecular weight and/or the degree of the polymerization of these pharmaceutical excipients, and (2) the ionization state of the model compound.We sought to demonstrate the usefulness of the T2 relaxation behaviors measured by time domain NMR (TD-NMR) for the quantitative evaluation of the crystallinity of an active pharmaceutical ingredient (API). This study used indomethacin as a model API. After blending amorphous and crystall
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