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Furthermore, it showed an IC50 = 0.53±0.8μM in cell viability tests on breast cancer cell line MCF-7, together with a good selectivity over non-cancerous HEK293 cells. Thus, 3b was selected as a potential PET tracer to study retinoids in vivo and the radiosynthesis of [18F]3b was successfully developed. Unfortunately, the stability of [18F]3b turned out to be insufficient for pursuing imaging studies.Gene drive is the process of copying of an endonuclease-containing cassette that leads to increased frequency of inheritance of the desire