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n of E. coli strains either with or without virulence factors was not associated with diarrhea in pre-weaned calves.An amendment to this paper has been published and can be accessed via the original article. Microglial polarization is a dynamic response to acute brain hypoxia induced by stroke and traumatic brain injury (TBI). However, studies on the polarization of microglia in chronic cerebral circulation insufficiency (CCCI) are limited. Our objective was to investigate the effect of CCCI on microglial polarization after chronic brain