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Key Findings The MS rats displayed obesity, hypertension, polydipsia, glucose and lipids metabolism disorders, increased inflammatory cytokine, hepatic muscle morphological and functional damage, additionally the up-regulated expressions of ERS-related, autophagy-related proteins and p-mTOR, therefore the down-regulated phrase of p-AMPKα. All aforementioned abnormalities in MS rats had been ameliorated in MS + CIHH rats. Value in summary CIHH

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