https://www.selleckchem.com/pr....oducts/sar131675.htm
The advent of hundreds of new compounds aimed at the substance misuse market has posed new analytical challenges. A semi-quantitative liquid chromatography-high resolution mass spectrometry (LC-HRMS) method has been developed to detect exposure to two novel stimulants, mephedrone and ethylphenidate, and selected metabolites. Centrifuged urine (50 µL) was diluted with LC eluent containing internal standards (mephedrone-d3, methylphenidate-d9, and ritalinic acid-d10, all 0.02 mg/L) (450 µL). Intra- and inter-assay accuracy and precision