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Results the outcomes had been generally in accordance with known in vitro and/or medical drug-drug interacting with each other information. Single-dose rifampin enhanced rosuvastatin area underneath the plasma concentration-time curve up to the last measurable concentration (AUC0-tz) by 248per cent and optimum plasma focus (Cmax) by 1025%. Probenecid increased furosemide AUC0-tz by 172% and Cmax by 23%. Cimetidine reduced metformin renal clearance by 26%. The effect of single
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