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Medical assessment for COPD included questionnaires, pulmonary function testing and calculated tomography (CT) imaging. Phenotypes had been tested for connection with SERPINA1 genotypes collated into four teams regular (MM), mild (MS and MI), intermediate (heterozygote MZ, non-S/non-Z/non-I, compound IS, and homozygote SS), and serious (ZZ and SZ) deficiency. Smoking strata and MZ-only analyses were also performed.Thirty-four genetic variants were identified includ
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