https://www.selleckchem.com/pr....oducts/crenolanib-cp
Bile duct ligation (BDL) in rodents can cause impaired liver function and cognition deficits. Curcumin has shown a preventive and therapeutic role in memory impairment. Therefore, this study aimed to explore the effect of curcumin on the performance of male adult Wistar rats that underwent BDL, a model of hepatic encephalopathy (HE) in the Morris water maze (MWM). Four weeks after surgery, sham (manipulation of common bile duct without ligation) and BDL rats underwent the MWM test. The representative data showed that BDL ra