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The PGE treated follicles revealed a reduction in the attributes of apoptosis in granulosa cells while PGF showed an increased in the apoptotic characteristics. The present study depicted that granulosa cell viability is dependent on the continuous supply of survival and growth factors and prostaglandin of E series synthesis is a crucial step in the suppression of granulosa cell apoptosis while that of F series induces apoptosis. The present study depicted that granulosa cell viability in vitro is dependent on the continuous supply of s

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