https://www.selleckchem.com/pr....oducts/napabucasin.h
tPNPs achieved high aqueous solubility of CFZ (1mg/mL), sustained drug release (t = 6.46h), and EpCAM-mediated cell targeting, which resulted in increased intracellular drug accumulation, prolonged proteasome inhibition, and enhanced cytotoxicity of CFZ in drug-resistant DLD-1 colorectal cancer cells. tPNPs improved stability and efficacy of CFZ in vitro, and these results potentiate effective cancer treatment using CFZ/tPNPs in future vivo studies. tPNPs improved stability and efficacy of CFZ in vitro, and these results potent
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