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The final analysis included a total of 5411 patients with epilepsy and 21,644 participants without epilepsy. The epilepsy group had significantly higher risks for development of MI (hazard ratio [HR], 1.71; 95% CI, 1.62 to 1.81; P.001) and arrhythmia (HR, 2.11; 95% CI, 1.97 to 2.25; P.001) and the occurrence of sudden death (HR, 1.83; 95% CI, 1.53 to 2.18; P.001) compared with the nonepilepsy group. Our results indicate that the risks for development of MI and arrhythmia and the occurrence of sudden death were higher in patie
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