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42± 5.5, which had significant difference ( =4.383, 0.001). There was no correlation between cold pain of knee and K-L grading( =2.138, =0.907). There was correlation between BME grading and degree of cold pain in observation group( =19.709, 0.001), and Spearman correlation coefficient was =0.509( 0.001). The cold pain of KOA patients is not related to K-L grading, but corelate with BME grading. The Cold pain of knee was more pronounced in KOA patients with BME, and the severity of BME is often related to degree of cold pa
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