https://wye354inhibitor.com/mu....lti-laboratory-evalu
Right here, we show that hippocampal neurons in six-month-old transgenic mouse model of tauopathy, THY-Tau22, are enriched with oligomeric tau, contain elongated mitochondria, and screen cellular stress, but no overt cytotoxicity compared to the control mice. The levels of a few crucial mitochondrial proteins had been markedly different involving the THY-Tau22 and control mice hippocampi such as the mitochondrial SIRT3, PINK1, ANT1 and also the fission protein DRP1. DNA base excision
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