https://hdacinhibitors.com/ind....ex.php/a-new-compreh
The plasmid-mediated, colistin-resistant gene mcr-1 has broken through the ultimate protection line against MDR Gram-negative pathogens. There was an urgent need certainly to discover the new chemical intended for colistin-resistant E. coli. In this research, anti-bacterial targets of ellipticine hydrochloride (EH) had been confirmed by localized surface plasmon resonance (LSPR) and decatenation assay. The LSPR analysis displayed good binding between EH and E. coli topoisomerase IV. I
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