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periodontal ligament, alveolar bone and cementum) and poor self-healing capability. In situ tissue manufacturing has emerged as a promising strategy that combines frameworks with development facets being especially chosen for the recruitment of endogenous stem cells towards the site of injury and to stimulate the innate regenerative potential of this human body. Herein, a core/shell fibrous super-assembled framework (SAF)-based sequential development aspect distribution system is developed, b
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