https://www.selleckchem.com/pr....oducts/bay80-6946.ht
miR-942 negatively regulates PPARγ expression via targeting the PPARγ 3' UTR. Inhibiting PPARγ promoted TGFβ induced HSC activation, and this effect was blocked after inhibitor the miR-942. Moreover, miR-942 was mainly expressed in fibrous septa and negatively correlated with PPARγ in liver fibrosis. SIGNIFICANCE PPARγ targeting by miR-942 and decreasing HSC activation in human hepatic fibrosis. Hence, regulating PPARγ may be a promising therapeutic strategy for hepatic fibrosis. INTRODUCTION AND OBJECTIVES The SAFEHEART study was de
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