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Certain friction coefficients approached those of unaffected normal equine SF. Induction of OA also caused synovial hemorrhage at 17 days, which was lower in joints treated with HCSG. After induction of OA, equine SF lubricant function was impaired. Hyaluronan-sodium chondroitin sulfate- -acetyl-d-glucosamine injection restored lubricant properties at certain time points and reduced pathological joint changes. After induction of OA, equine SF lubricant function was impaired. Hyaluronan-sodium chondroitin sulfate-N-acetyl-d-glucosamine i
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