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With no evidence of viral or autoimmune liver disease, SSC induced by lapatinib and vinorelbine was diagnosed. This is the first case report of tyrosine kinase inhibitors and vinorelbine induced SSC and clinicians should be aware of the possibility of it. More case reports about this adverse drug reaction are needed to delineate optimal management.One nucleotide substitution in codon 57 of HLA-A*31010201 results in a novel allele, HLA-A*31195.The increasing number of measurable markers and the need to integrate flow cytometry datasets wit
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