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In this review, the authors discuss the available data regarding the use of peroral cholangioscopy in patients with PSC, with a focus on its use in the evaluation and management of biliary strictures and stones.Helicobacter pylori has several virulance factor i.e. VacA, CagA, BabA, SabA, AlpA, AlpB and etc. VacA has several polymorphic region in the nucleotide sequence such as s,m,i,d and, c. It has been suggested that each variation in these polymorphic region has been influenced the toxicity of VacA toxin. We performed a comprehensive
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