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In addition, the metabolomic profile of sEVs was observed to change under hypoxic stress, and an increase in metabolites involved in angiogenesis was also detected. We reveal the hallmark of the metabolites contained in sEVs and the effect of tumor hypoxia on their profiles, which may help in understanding EV-mediated cancer malignancy.External causes of injury are major contributors to mortality among people with disabilities. We analyzed the 10-year trend (2008-2017) of mortality attributed to external causes of injury among people wit

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